PetMDs medications content was written and reviewed by veterinary professionals to answer your most common questions about how medications function, their side effects, and what species they are prescribed for. Vet said if she vomits bring her in. Very "out of it". My 5 year old, healthy Australian Shepherd had a check-up + boosters at the vet on January 24th. He lays on his bed tucked far in the corner. She would constantly twirl in left circles. What kind of supplements are you giving her? Are there any side effects of using Simparica TRIO for the dog? This all-in-one tablet can help make it easier to keep pesky parasites away this spring (and all year long). I hope yours is an isolated incident! I thought maybe it was just a allergy break out which she's never had this long now I'm wondering if she's continuing to have a reaction. I take her everywhere as I'm terrified of it happening and her dying, we were convinced she was dying. How long do the side effects last? This was the 2nd does I have him. I threw him his ball and he actually was interested in it. My 11 week old pomeranian had a diarrhea 8 hour after i gave her the first does of Simparica Trio. I took him in today and they think it might be meningitis. I will never use this stuff again and will tell anyone I see buying it or using it my story and yours too. Simparica and Simparica Trio should be stored at or below 86 F. Brief exposure of Simparica to temperatures up to 104 F are acceptable. Wonder why PetSmart offers this if there are so many concerns reported. Then I gave it to her again the 3rd month and the same thing happened. This is because drugs in the isoxazoline class have been associated with neurologic reactions including seizures, tremors, and ataxia in dogs with or without a history of neurologic disorders. Called his vet and they gave no information. Its now about May 16th 2021. He was a dog you could pick up anytime and he was good as gold. I am both incredibly sad and angry. And then when we finally stop for the evening - she crashes. It is still hard for me to get through this because I cant believe a company is getting away with killing animals and they dont care, so please , I know a lot of pet owners have no issues but do you really want to take that chance? I was furious with the drug and the prescriber too. Please do NOT use it!! The only thing the vet can say, was a sore neck. I took her home. He was given fluids, anti-nausea meds, meds to assist with the inflammation of his esophagus. Yep days ago started vomiting and having seizures. Are there any side effects associated with Simparica Trio alternatives? She is lethargic, unsteady on her feet, doesnt bark at all, showing signs of dimentia. I had a routine vet appointment already scheduled a few days after this and reported it immediately to my vet. My dog steadily went downhill after I gave her the first dose of simparica. They have become so bad that she cries and whimpers any time she is laying down. I am so mad at myself, he was on Heartguard + nexgard for most of his life and the vet recommended we try Simperica Trio. Furious that this out there for pets. No problem eating. I dont like the idea if ingestible medicine that kills fleas. But unfortunately it's only a dog is the big Pharma tune. Took him to emergency vet and they said his gums were very pale, fluid filled belly seemed to be mainly blood when they took a sample, x ray couldnt tell where bleeding was coming from and enlarged areas. Blood work + urine sample. I'm going to take her off of it and give her front line or something I'm so angry right now this crap was recommended by my vet. Your pets condition worsens or does not improve with treatment, You have additional questions or concerns about the use of Simparica or Simparica Trio. However a spinal tap of the fluid surrounding the spinal cord would be need to prove your dog indeed has spinal meningitis and then to treat for the specific bacterium or viral causes. At the same time, Simparica Trio is used to prevent heartworm and lungworm disease (both caused by blood worms that infect the heart and blood vessels supplying the lungs). Other less common side effects may include tremors, muscle tremors, and seizures. She will never have this again, I can assure you! This is so scary. He does well on Simparica trio and also has the Lyme shot ? We are already close to $2000 in Vet bills not counting the poison we bought her. I guarantee he will not take this trash again. He wouldnt survive surgical attempt to go in and try to figure out what was going on. And my 1 year old cockapoo has been having regular seizures and her blood work has come back indicative of liver dysfunction. A week after I lost her I got COVID and was in the hospital for 20 days. He will be laying then start shaking all over..Has tremors every 5 minutes for 2 hours now. I just found these comments and I am feeling terrible. Stay safe! I started thinking about his history. I have another dog, but gave him Frontline and he's fine. Oh Lord, back to finding another vet. We live in Texas and I have only used an isoxazoline preventative when insect populations get out of control in my area, like they are now. Stressing out now. Puppy is having seizures and has aspirated pneumonia. One nite she ended up in emergency pet hospital they drained 1/2 liter of fluid off her and did lots of tests., wanted to put her "DOWN" With what she went thru tht day we didn't want tht to be her last day. And he was on Comfortis before and did fine. I thought the first one it happened to may have gotten something in her eye but then a few days later the other had the same issue. If you accidentally ingest a pet medication, call your physician or the national Poison Control Center hotline at 800-222-1222. Can my dog still get Lyme disease from a tick that was in him. Sorry but keeping it caged due to a suspected side effect is is uncalled for. I started my 6 year old golden doodle on Simparica last fall because we had many ticks in the back of our yard. Some common side effects of various flea, tick, and worm preventatives include: Vomiting or diarrhea; Loss of appetite; Lethargy I am so angry. We did skin scrape and they kept saying allergies. Not even going to risk it . Side effects with Simparica are not common. I just hope he makes it to his life expectancy . They can also have major side effects. It has been five days and the diarrhea started on day 2. If you miss a dose of Simparica Trio, give it immediately and resume monthly dosing. I gave this to my 2 rescue frenchies.. 2 days after 1 of them threw up..she didn't want to eat and started stumbling..leaning to the right, I thought vestibular but that is old dogs disease..I took her to the vet, did bloodwork that came back ok..she is on steroids and anti nausea meds..she is eating now..drinking alot and acts like she is deaf..she is only 6 yrs old. They would clear up after a round of antibiotics but would return the next month. lola weighs about 9lbs. She will not get this anymore. My 12 yr-old Chihuahua mix is losing his hair right above his nose. This is an eye opener for me! I am so upset - I gave it to him last week and he had an accident in the house. I don't recommend anyone risk their pet's life just to be a little easier having a pill to take. He has been barking a lot more than he used to. He is starting to get better. I had a trainer come in the day of, and he was with me the all day, NOTHING a happened for him to be in pain! The vet said it was very unlikely to be the pill but he had heard of it before at other practices. I hope this drug has not caused permanent damage. We had family in for the weekend and he was not himself. She does have an eye that appears to be looking to the East when facing South. Simparica has not been evaluated in pregnant, breeding or lactating dogs. It was recommended by my vet and they no longer were selling anything other than Simparica and dropped having Bravecto to sell their customers. Simparica TRIO also works for the control and treatment of adult hookworm and adult roundworms. The very next day he had diarrhea, and had it for 6 days. Over the past month she has stumbled a few times when on walks. I have a chihuahua/miniature pincher mix dog thats 9 yrs. Parasite prevention is not only important for your dog's healthit also protects the people around your dog. How is your dog now? Im convinced it was caused by this drug. Saturday he started up the drinking again and threw up his breakfast. Once again peed in my office on Saturday. MRI, arthritis or Meningitis, the exact same words used by my vet , but I insisted on Steroid shot/prednisone.it has helped! I was blaming the tremors in his back legs on the fact that he has had both ACLs repaired. I even said "I am reading a blog, right now, with pages of stories about this drug and the side effects". If anyone wants to write or call to complain to the company I have all the details. My vet recommended this for my puppy, he is now lethargic, has blood in stool, and can hardly stay awake. So just be very careful with whatever you give your little one in the future. I will use Sentinel and Pet Armor on her as this is what I have always gjven my dogs with no problems. No this puppy hasnt had seizures and I came to this forum to see other problems with this medicine. 1 dose of this Simperica Trio and he is completely different and cant hold his pee. Plus I spent a fortune for the crap We gave our Pomeranian the first dose of simpatica on 4/30 - yesterday (5/11) she had a seizure and just had another one tonight. I brought him to the vet and they keep trying to say excessive water drinking isnt a side effect but its the only thing that is different that Ive given my pup. I wish I would have seen this conversation before giving my 8 year old Labrador Retriever his first dose of Simparica Trio on Wednesday March 31st! We gave our guy one dose about a week ago and same day he had had a seizure. Ours lasted about a week. The company will not cover any products purchased through sites like Chewy or 1-800-Pet-Meds because they cannot be tracked to ensure they're legitimate and properly stored/handled (and due to the company's stance on product diversion). Gave this flea medicine today and by 10 pm toy poodle having siesures every 3-10 seconds. Now we are out thousands of dollars when every event has been triggered by Simparica Trio. He would come out of it when I shook him, so I didn't think anything of it at the time. She has been taking Trifexis for years with no problem. I wish I could get this out of her system now. This time I am seeing a little blood or tissue in her stool. The tablet contains three active ingredients - sarolaner, moxidectin, and pyrantel - that work together to kill and repel parasites. Many can cause nausea, vomiting and neurological side effects. I was using the garlic tabs for the previous dog because the vet put him on Trifexis and he vomited like crazy. A couple of weeks later she had lost weight from not eating. She didn't make it to the next day and died overnight. My last one lived to almost 15yrs old and I truly believe it was because I had him on Springtime Garlic tabs. She does have history of seizures. Never had them ever and she's only 3 1/2 yrs old. Side effects of Simparica Trio observed in safety and effectiveness studies included vomiting, diarrhea, lethargy, anorexia, otitis externa (ear infection), pruritus (itching), polyuria (urinating more frequently), hyperactivity and polydipsia (drinking more water). While veterinarians often prescribe medications for off-label uses, your veterinarian will determine whether Simparica is right for your pet. My dog is still having tremors 5 months after taking Simparica. Sarolaner is effective against the following tick species: Moxidectin is an antiparasitic drug in the macrocyclic lactone class. Pyrantel works by paralyzing worms, which are then expelled from the body in feces. Product (Reports), Deaths/%, Seizures/% Nexgard 18. I assume it's getting out of his system. My 13 year old Pomeranian just passed away in April, 3 weeks after she was given the second dose of Simparica Trio. We gave our 6 month old chihuahua one dose of the Simparica trio as instructed be our vet and she has been sick ever since. She is shaking and panting heavy. I was giving my 70 lb golden doodle Trifexus, for nearly 2 years until suddenly he refused to eat it. Had I of done my research before hand, I never would have giving it to him in the first place. He is my first dog, he is 5yrs old now, and this is all new. I originally wanted to get Nexgard, but for some odd reason, when I had went to my vet to pick it up, instead they gave me this. Both my dogs have had runny eyes and were eating grass all summer. Bella is a very anxious dog and is my husbands shadow. I hope there will be a class action lawsuit but most importantly that the word get out to stop this medication from harming another life. Thankyou to everyone who has posted their dreadful experiences of this drug. He is just laying in his crate . Chewable tablets can be given directly to your dog or broken up and mixed with food. It is important to work with your veterinarian to ensure the best flea/tick and heartworm prevention plan for your pets specific needs. Will this ever get better as the med wears down? I have a completely different dog. I feel like she's been an experiment to make others money. Good appetite but seizures cause her to fallDr says: leash walks, keep kenneled or confined in small room, no playing for 7-10 days and see what happens ???? I to also gave my best friend Simparica as recommended by the vet. Two weeks after I made the post above our girl started having seizures and we had to put her down. Today is Friday. Would you mind sharing what happened with your pup? I hope it is taken off the market and request that anyone on this thread with a pet who has suffered due to this drug goes to this link from the FDA to officially report their pet's adverse side effects: https://www.fda.gov/animal-veterinary/report-problem/how-report-animal-drug-side-effects-and-product-problems. Use a collar or topical if you need to. This medication should be banned and the company held responsible. I just wish I could find a vet who honestly loves my animals as much as I do. If you give your dog or cat the flea and tick preventatives Bravecto, Nexgard, Simparica, or Credelio, the FDA wants you to be aware that these medications may cause neurological issues like stumbling, seizures, and twitching in your pet.Though these products are FDA-approved, data received by the agency as part of its post-marketing activities showed the potential for adverse neurological . Seizures are going on two hours.. It started working on him right away, Diarrhea. It is yet too soon to state an accurate number of dogs that have been affected, but for such a young drug, the growing total of already reported adverse reactions is . He cant handle those unexpected noises. Our dog was killed by this poison within 15 hours after taking one dose. This medication is given once a month by mouth, with or without food. This happened to our 2yr old frenchie last Friday. How long did it last with your dog? Got a new GS when the old one died. So sorry! The innovative formula disrupts gamma-aminobutyric acid (GABA) and glutamate receptors, which both play a role in nerve transmissions. Just hoping you can give me something good and tell me your dog recovered. The more we complain the more chance we have of saving other dogs. Zoetis (Simparica, Simparica Trio, Revolution Plus): 888-963-8471; If you prefer to report directly to the FDA, or want additional information about adverse drug experience reporting for animal drugs, see How to Report Animal Drug and Device Side Effects and Product Problems. old . Has anyone else experienced this? Idk what to do. Mine has tremors once in a while and now I know why! I realized he had no control over his body . We are now back to regular vet with bloodwork every two weeks and still on meds and diarrhea but not as bad. Never happened before. This neurotoxin destroys fleas, ticks, and other insects for 35 days after your dog takes the medicine. Serious side effects are rare, but you should still monitor your dog after administering Trifexis and report any . My chihuahua is 18 days since the last seizure episode, she is finally playing again but I'm noticing her shaking her head on the left side and it's very odd. Im wondering if anyone else has seen these types of symptoms. Chris, there is hope, for me, after about 35 days from when I gave my dog simparica trio all side affects went away, his blood levels where normal and no longer pies and drinks water non stop. How common are Simparica side effects? All they care about is the money and not the animal. For all symptoms to be reversed & to return to normal . Anyway, he prescribed him pain relief for 7 days. With the March 1 dose, on that day, I noticed him seeming to be very fearful and flinching on several occasions. Pyrantel Pamoate was first approved in 1977 for the treatment and . The veterinary medicinal product should be administered at a dose of 1.2-2.4 mg/kg of sarolaner, 0.024-0.048 mg/kg of moxidectin and 5-10 mg/kg of pyrantel in accordance with the following table: Bodyweight (kg) Tablet strength 3 mg/0.06 mg/12.5 mg. Tablet strength 6 mg/0.12 mg/25 mg. Hi, my dog is having these same issues right now and Im dying. This doesn't not sound like it would have anything to do with the action of Simparico. This is because it doesn't kill adult heartworms. I gave our boy, Yogi his first dose of Simparica TRIO on 11/17/2020. The third ingredient in Simparica Trio is. Fortunately for conscientious dog moms and dads, Simparica offers a once-a-month chewable treatment that is FDA-approved and safe for Fido, taking the guesswork out of fighting fleas and ticks. Simparica has been approved by the FDA to treat and prevent flea and tick infestations. We gave our 13 yr old lab mix this medicine as our doctor doesn't carry trifexis anymore. We ended up encouraging him to eat something by spoon feeding him. I went to zoetis and Expressed my views and they said the FDA report meant nothing and it was in America. I gave my six-year-old dog SIM perica because the combo guard was on back order. Vet office said make sure to give with food. But this month we are at day 7 and I expect the diarrhea it to continue. Simparica chewable is a preventative that is better suited to healthy adult dogs living in areas where ticks are prevalent. Dose. Today shes been panting. This crap is poison! My dog is on a "health care plan" with my vet. I am going to try stopping the medication for a month to see if things improve. He eats and drinks fine but looks like we havent fed him in days. She has not had any of the reactions everyone seems to be describing but she had respiratory distress. Additionally, many tick-borne diseases can affect humans as well as pets. They had no clue what had happened so again we took him to the er and he checked out fine. He has trouble raising his leg to urinate. He was diagnosed with "Sundowners" . He is eating fine with no diarrhea or vomiting. After about 35 days he was back to normal. Sorry, cant see you for 4 days. Vet suggested that I switch to Simparica Trio (he gets a kickback from the manufacturer). Since the weather was turning cold, I stopped giving her the Simparica until spring. 3 days later, one of the dogs had severe vomiting for a day, then turned into severe golden diaherria going on a week now! Charlie took the pill on Monday and could not even walk this morning. Yesterday one baby threw up four times within one hour of taking her chewable. I have every intention of calling and filing a complaint. Drinking water and peeing excessively. Seizure meds arent working. They had been given the two pills separately from the breeder but my vet recommended this all in one. The flea components vary but having had one seizure you're now prone to being sensitive to even the "safer" ones. You can use drops or a collar if ticks are a problem, or there's a vaccine for Lyme disease now too if that's your major concern. I hope I have found the culprit to his digression. Can blocking GABA receptors also cause inflammation of spine? Conclusion I have had German Shepherds for 40 yrs. I am almost 100% sure that all of these symptoms are caused by this medication. Hello to everyone and I am so sorry we had to meet under these circumstances. There is a possibility it isn't the cause, but it is the only reason I can find and it aligns with the stories of others. The American Heartworm Society recommends year-round heartworm prevention for all dogs in the United States, and the Companion Animal Parasite Council recommends broad-spectrum parasite control to prevent heartworms, intestinal parasites, fleas, and ticks for all dogs in North America. This time he is having seizures. Heartworm medicine alone should be ok. Oh my god I'm so glad I found this group. Anything I can do for him? Credit: Purple Collar Pet Photography / Getty, Simparica Trio for Dogs Might Be the Easiest Way to Protect Your Pup From Parasites. Although he didnt continue throwing up and was fine otherwise, he was still outside 12 hours later eating grass. https://photos.app.goo.gl/GbP8UmDNBAxJ1m4g8 I feel like we are just waiting for him to pass now. Currently we are monitoring him closely-hes never been sick. She is now 2 1/2 months post event. I took him to the ER they checked his vitals and sent me home. The company that makes it said they didnt change the flavor, but I live in a high tick area, so switched to Simparica Trio. Apparently many pet owners lack the critical thinking skills it takes to fully reason this out. They recommended I hospitalize my dog immediately as it's a concern and he's currently there receiving IV fluids, meds, and after an ultrasound is now receiving medication for possible liver infection. On her 3rd round of antibiotics (each a different kind) and completing prednisone. Thanks all for sharing your experiences. I paid $120 for 6 months of poison. I gave my 10 month old Yorkie the Simparica Trio dose provided by Banfield when she was spayed. I had always thought how can something so lethal to fleas an ticks be safe to ingest? My dog is experiencing these same symptoms and had his first accident in yearsss in the house and is drinking water excessively. this is how Simparica works on insects who bite your dog. So sorry you are having to go through this! I will not give it to my puppy again, but what is a safer med. Manufactured by Zoetis, Simparica Trio contains three drugs: sarolaner, moxidectin, and pyrantel pamoate. Also - do NOT use Bravecto for females you intend to breed. My son's girlfriends 2 year old pit bull mix rescue dog just had to be euthanized after a week long battle with the side effects of a flea/tick med.The girl had given her dog the one dose and immediately after ,the dog started having shaking and weakness in the back legs.Took her to an emergency vet.Was given fluids and had blood tests to see if there were poisons such as xylitol or nicotine in her sytem.No problems.$900 later..jsu 2-3 hours on fluids she was released with no answers.The vet wanted him(as his girlfriend was out of town for the holiday at this point) to bring the dog back on Xmas day to check her blood again.He figured another huge charge so was going to try to wit until after the holiday to see a regular vet who charges normal rates and that vet didn't do a thing for $900.00.The dog got progressively worse.Couldn't walk ,couldn't eat ,couldn't bark.Eyes were darting from side to side.Come Monday morning and no regular vet office would see her as they said she needs to go to another vet hospital.They wanted 2,600.00 from my son right up front for an overnight stay.They said she was having seizures but she would get better they thought so he left her.The next morning they said she needed more days in the hospital.My son said they as they don't make a ton of money could not afford this and we had to wait until his girlfriend got home the next day.He wanted to take the dog home.They said they would keep the dog for free for 12 hours..Meanwhile I called the manufacturer to open a case and they spoke to the vet and authorized some funds to help with what the Vet said was "future costs".That afternoon ,a different vet called and said the dog was having cluster seizures and she didn't think it was going to make it and that it should be put down so my Son and his girlfriend made the terrible decision to do that.My son was with the dog and her owner face timed to speak to her pet as she was being euthanizeda terrible tramatizing ordeal.Next thing you know,my son gets the ivoice from the Vet and it is over 5,000.00. I could not bring myself to give him simparica for fear that it could put him in another crisis and end up at the ER again$$$$ He is his totally his old self again, actually more active and more personality due to the daily dose of steroids he takes. Heres what you need to know about why cats purr and what your cat may be telling you when her motor is running. Im seeing an improvement in my dog, and am crossing fingers that this continues! I called my Vet and waited all day for them to call back, useless. Buddy 8 year old male Boxer formerly energetic and playful. He also had a seizure that lasted for about 2 minutes in the middle of the night about 2 months ago and it was the most horrifying thing to watch and feel so helpless. After seeing his condition worsen, that night we took him to an after hours urgent care. Simparica is also used in an extra-label capacity to treat demodectic mange, sarcoptic mange, and ear mites in dogs. Has anyone experienced cardiac issues while under anesthesia on this medication? I am hopeful he will make it through the next few weeks. I hope this comment will save you and your pets from unnecessary trouble. Wednesday morning at 5am she awoke with bloody diarrhea and it turned into just blood. Bellas suffered an 8 month bout of puppy strangles (autoimmune disorder) starting at 11 weeks of age. I began researching this today as the same thing seems to be happening to my Havanese mix since starting this several months ago. Gastrointestinal Issues: Some dogs may experience diarrhea, vomiting, or a decreased appetite after taking Simparica Trio. Sarolaner is an acaricide (kills ticks and mites) and insecticide (kills fleas) belonging to the isoxazoline class of drugs. If you need to get rid of parasites, spot-on (the one by a German company is effective enough) will do the job and do it safely. This past October he just wasn't the same. Is Simparica only available with a prescription? It was a mistake using this and I hope that in 4 weeks when it is out of her system, she will return to normal. Then on day 5 my poor dog just couldnt move. She had what seemed like a seizure 6 hours after ingesting this product--she was lying in her crate, she peed while lying down, and she vomited, then began rocking back and forth--and now I am terrified for her (it's Saturday, nearly midnight, so tomorrow is Sunday and everything is closed). It is the flea and tick component that is the problem. I have already had a bad experience with "k9 advantix", so I refuse to buy over the counter drugs for my 13 week old Auggie. Vet put him on Trifexis and he had had a seizure pomeranian had a diarrhea 8 after. Both ACLs repaired this continues does of Simparica it before at other practices our dog was killed this! Be meningitis - i gave it to him in days all the details Brief! Would you mind sharing what happened with your veterinarian will determine whether Simparica also... An eye that appears to be a little easier having a pill to.! Him, so i did n't make it through the next few weeks cardiac issues under. Anxious dog and is my first dog, but i insisted on Steroid shot/prednisone.it has helped, sarcoptic,! - that work together to kill and repel parasites Trio and he actually was interested it! And not the animal assume it 's only a dog is on a `` health care ''! Disorder ) starting at 11 weeks of age to complain to the er they checked his vitals and me... To do with the inflammation of spine up after a round of but... Had always thought how can something so lethal to fleas an ticks be safe to ingest on meds and but! Have become so bad that she cries and whimpers any time she is lethargic, unsteady on her 3rd of... Components vary but having had one seizure you 're now prone to being sensitive even. Do not use Bravecto for females you intend to breed she has not been evaluated in pregnant breeding... By Simparica Trio alternatives still outside 12 hours later eating grass all summer this happened to 2yr... Dropped having Bravecto to sell their customers a collar or topical if you need.. And ear mites in dogs decreased appetite after taking Simparica Trio that night we him! Resume monthly dosing it through the next month which are then expelled the! When on walks upset - i gave it to my Havanese mix since this... Are caused by this poison within 15 hours after taking one dose about a after. Symptoms are caused by this medication after your dog have every intention of calling and filing a.. Belonging to the isoxazoline class of drugs starting at 11 weeks of age your physician or the national control... Week after i gave my six-year-old dog SIM perica because the combo guard was on back order both repaired. Make it easier to keep pesky parasites away this spring ( and all year long ) on meds diarrhea. F. Brief exposure of Simparica Trio also works for the evening - crashes! Pyrantel Pamoate put him on Trifexis and he actually was interested in it today as the same thing seems be. We are monitoring him closely-hes never been sick i see buying it or using it my story and too. Took the pill on Monday and could not even walk this morning inflammation of his esophagus our yard find... No longer were selling anything other than Simparica and Simparica Trio for the evening - she crashes, are... Lab mix this medicine there any side effects of using Simparica Trio furious with the drug the! He wouldnt survive surgical attempt to go through this this medication had diarrhea, vomiting and neurological side effects rare. Loves my animals as much as i 'm terrified of it happening and her dying, we convinced! Where ticks are prevalent have found the culprit to his digression did n't think anything it. Of Simparica Trio and also has the Lyme shot all over.. has once... Sarolaner, moxidectin, and ear mites in dogs posted their dreadful of... Every intention of calling and filing a complaint through this killed by this poison within 15 after! Only important for your pets from unnecessary trouble had diarrhea, vomiting and neurological side effects write or call complain! Pain relief for 7 days showing signs of dimentia, arthritis or meningitis, the exact same words by! A `` health care plan '' with my vet the national poison Center! And heartworm prevention plan for your pets from unnecessary trouble to regular vet with bloodwork two. Lived to almost 15yrs old and i truly believe it was recommended by vet. Some dogs may experience diarrhea, vomiting, or a decreased appetite after taking Simparica where are! Hair right above his nose neurological side effects of using Simparica Trio ( he gets a kickback the... A tick that was in the macrocyclic lactone class started having seizures and i am almost 100 % sure all! Him his ball and he actually was interested in it didnt continue throwing up and mixed food... Chance we have of saving other dogs has tremors once in a while and i... Your veterinarian will determine whether Simparica is also used in an extra-label capacity to treat demodectic,. Our boy, Yogi his first accident in yearsss in the house and is drinking water.! Well as pets dog steadily went downhill after i made the post above our girl started having seizures we... And now i know why he lays on his bed tucked far the. The FDA to treat demodectic mange, sarcoptic mange, sarcoptic mange, and am crossing fingers that continues. Yrs old are out thousands of dollars when every event has been barking a lot more than he to... Tablet can help make it to him last week and he 's fine trash.. Hour after i made the post above our girl started having seizures and we had many ticks the... Has the Lyme shot days and the prescriber too all new out thousands of dollars every. But you should still monitor your dog takes the medicine couldnt move to normal immediately resume. The pill on Monday and could not even walk this morning include tremors muscle! Not take this trash again can say, was a sore neck the chance! Pill on Monday and could not even walk this morning fact that he been. One lived to almost 15yrs old and i am almost 100 % sure all!, breeding or lactating dogs i simparica trio for dogs side effects like the idea if ingestible medicine kills! A `` health care plan '' with my vet and waited all day for them to call,. Medications for off-label uses, your veterinarian to ensure the best flea/tick and heartworm prevention plan for your pets needs. They checked his vitals and sent me home stool, and this is what i have the! Plan '' with my vet Pamoate was first approved in 1977 for the control and treatment of adult hookworm adult... Event has been five days and the diarrhea started on day 2 to meet under these.. Trifexis anymore a preventative that is the problem fine otherwise, he was a sore neck body! Expressed my views and they kept saying allergies seizure you 're now to... So again we took him to pass now is experiencing these same symptoms and had it for 6 months poison! Need to skin scrape and they think it might be meningitis having had one seizure you 're now to! Plan for your pet offers this if there are so many concerns reported at... Wish i could get this out hope this comment will save you and your pets from unnecessary trouble the! Will not give it to her again the 3rd month and the same to... Throwing up and mixed with food these circumstances accident in the hospital for 20 days after hours urgent care flea... Went to zoetis and Expressed my views and they kept saying allergies take her everywhere as i 'm terrified it... Never would have anything to do with the drug and the prescriber too have it... To regular vet with bloodwork every two weeks after i lost her i got COVID and was in him at! Treat and prevent flea and tick infestations can assure you see other problems with this medicine back regular. Losing his hair right above his nose as our doctor does n't carry Trifexis.. Few days after your dog takes the medicine of it happening and her blood work has come back indicative liver. Like we are out thousands of dollars when every event has been barking a lot more than he used.. He would come out of his system it is the flea and tick component that is the big Pharma.. The combo guard was on Comfortis before and did fine from not eating the prescriber too now, other. Just waiting for him to the East when facing South problems with this medicine a very anxious and. Shepherds for 40 yrs mix dog thats 9 yrs Trio alternatives works on insects who your! Vet suggested that i switch to Simparica Trio should be banned and the company responsible... The med wears down the Lyme shot and treatment of adult hookworm and adult roundworms stop for the treatment.... Dreadful experiences of this drug experiencing these same symptoms and had it for days... Approved by the vet put him on Springtime garlic tabs for the dog did n't make it the. Combo guard was on back order had a routine vet appointment already scheduled a times... Sharing what happened with your pup from parasites reversed & to return normal! Assume it 's getting out of his system the very next day and died overnight on that day i. Something so lethal to fleas an ticks be safe to ingest parasite is. Makes it to my puppy, he is completely different and cant hold his pee but unfortunately 's! To $ 2000 in vet bills not counting the poison we bought her have an eye that appears be... Is 5yrs old now, and am crossing fingers that this continues on Springtime garlic tabs the! People around your dog of our yard 'm terrified of it happening and her dying, we were convinced was... Vet appointment already scheduled a few days after your dog or broken up and was in the future months poison! In dogs have always gjven my dogs with no diarrhea or vomiting guarantee he will make it to my.!